SCHEMBL28958476

SCHEMBL28958476

O=C(O)C1CCC(CCC2CCC(C(=O)O)C(C(=O)O)C2)CC1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
PLG P00747 1/20 0.43
PLAT P00750 1/20 0.43
GABRR1 P24046 5/20 0.40
SLC1A2 P43004 3/20 0.40
SLC1A1 P43005 2/20 0.40
GABRR2 P28476 1/20 0.39
PEPD P12955 1/20 0.39
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
GRM8 O00222 1/20 0.37
GRM6 O15303 1/20 0.37
APEX1 P27695 1/20 0.37
GRM5 P41594 1/20 0.37
PMP22 Q01453 1/20 0.37
GRM1 Q13255 1/20 0.37
GRM2 Q14416 1/20 0.37
GRM3 Q14832 1/20 0.37
GRM4 Q14833 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8460803 0.87 TLR4 (0.38) LMNAPLGPLATGABRR1GABRR2
SCHEMBL14972605 0.85 PLG (0.43) LMNAPLGPLATGABRR1SLC1A2
SCHEMBL30922213 0.85 TLR4 (0.37) LMNAPLGPLATGABRR1GABRR2
SCHEMBL29282893 0.85 TLR4 (0.37) LMNAPLGPLATGABRR1GABRR2
SCHEMBL29282877 0.85 TLR4 (0.37) LMNAPLGPLATGABRR1GABRR2
SCHEMBL8464399 0.83 MAPT (0.46) LMNAPLGPLATMEN1KMT2A
SCHEMBL30922235 0.82 MAPT (0.45) LMNAPLGPLATMEN1KMT2A
SCHEMBL28572525 0.82 MAPT (0.45) LMNAPLGPLATMEN1KMT2A
SCHEMBL28575027 0.82 MAPT (0.45) LMNAPLGPLATMEN1KMT2A
SCHEMBL28564111 0.82 MAPT (0.45) LMNAPLGPLATMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286596-A Novel diamine compound, polyimide precursor and polyimide film using the same, and use thereof SK新技术株式会社 2022-11-04 CN disclosed
CN-115215873-A Novel diazaspiro compounds and uses thereof SK新技术株式会社 2022-10-21 CN disclosed