SCHEMBL8460803

SCHEMBL8460803

CCCC1CCC(C(=O)O)C(C(=O)O)C1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.38
LMNA P02545 2/20 0.38
PLG P00747 1/20 0.38
PLAT P00750 1/20 0.38
CYP2C9 P11712 1/20 0.37
GRM2 Q14416 1/20 0.35
GRM3 Q14832 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
GABRR1 P24046 5/20 0.34
GABRR2 P28476 1/20 0.34
PEPD P12955 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29282877 0.98 TLR4 (0.37) TLR4LMNAPLGPLATCYP2C9
SCHEMBL29282893 0.98 TLR4 (0.37) TLR4LMNAPLGPLATCYP2C9
SCHEMBL30922213 0.98 TLR4 (0.37) TLR4LMNAPLGPLATCYP2C9
SCHEMBL8464399 0.88 MAPT (0.46) TLR4LMNAPLGPLATALDH1A1
SCHEMBL28958476 0.87 LMNA (0.43) LMNAPLGPLATCYP2C9GRM2
SCHEMBL30922235 0.86 MAPT (0.45) TLR4LMNAPLGPLATALDH1A1
SCHEMBL28564111 0.86 MAPT (0.45) TLR4LMNAPLGPLATALDH1A1
SCHEMBL28559884 0.86 MAPT (0.45) TLR4LMNAPLGPLATALDH1A1
SCHEMBL28575027 0.86 MAPT (0.45) TLR4LMNAPLGPLATALDH1A1
SCHEMBL28572525 0.86 MAPT (0.45) TLR4LMNAPLGPLATALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4764452-A BLEND OF MALEIC ACID-STYRENE COPOLYMER, HYDROXYL(OR TETRAHYDROFURFURYL) (METH)ACRYLATE, POLYALKYLENE GLYCOL ACRYLATE AND AN UNSATURATED CARBOXYLATED ESTER TAMURA KAKEN CO., LTD. (JP) 1988-08-16 US claimed
CN-115298254-B Modifier for polyolefin resin and polyolefin resin composition containing the same 新日本理化株式会社 2024-07-19 CN disclosed
CN-112714759-B Metal salt, crystallization nucleating agent composition, polyolefin resin composition, and polyolefin resin molded body 新日本理化株式会社 2023-12-12 CN disclosed
CN-115298254-A Modifier for polyolefin resin and polyolefin resin composition containing the same 新日本理化株式会社 2022-11-04 CN disclosed
CN-103713470-B Print resist activity energy-line solidifying type resin composition and its corrosion-resisting pattern 荒川化学工业株式会社 2019-09-24 CN disclosed
US-5916736-A HEXAHYDRO- OR TETRAHYDROPHTHALIC ACID MONOESTER WITH HYDROXY(ALKOXY)ALKYL (METH)ACRYLATE, TRANSPARENT ROSIN GOO CHEMICAL CO., LTD. (JP) 1999-06-29 US disclosed
US-5821279-A CATALYST, ROSIN, EXTENDER AND HYDROTHALIC ACID MONOESTER GOO CHEMICAL CO., LTD. (JP) 1998-10-13 US disclosed
US-4764452-A BLEND OF MALEIC ACID-STYRENE COPOLYMER, HYDROXYL(OR TETRAHYDROFURFURYL) (METH)ACRYLATE, POLYALKYLENE GLYCOL ACRYLATE AND AN UNSATURATED CARBOXYLATED ESTER TAMURA KAKEN CO., LTD. (JP) 1988-08-16 US disclosed