Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 3/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29177391 | 0.87 | MEN1 (0.46) | EPHX2MEN1KMT2APDE2AKIF11 | |
| SCHEMBL29177399 | 0.87 | EPHX2 (0.45) | EPHX2SLC7A5MEN1KMT2APDE2A | |
| SCHEMBL28351071 | 0.80 | EPHX2 (0.46) | EPHX2SLC7A5PDE2ASCN9ASLC6A2 | |
| SCHEMBL23518992 | 0.79 | EPHX2 (0.54) | EPHX2SLC7A5PDE2ASCN9AABL1 | |
| SCHEMBL27777720 | 0.79 | KMT2A (0.47) | MEN1KMT2AKIF11 | |
| SCHEMBL29177250 | 0.78 | EPHX2 (0.45) | EPHX2SLC7A5MEN1KMT2APDE2A | |
| SCHEMBL14506627 | 0.78 | EPHX2 (0.47) | EPHX2SLC7A5MEN1KMT2APDE2A | |
| SCHEMBL28954385 | 0.77 | KMT2A (0.46) | MEN1KMT2AKIF11SCN9A | |
| SCHEMBL27091691 | 0.77 | PIM1 (0.42) | EPHX2KMT2AKIF11SCN9ASLC6A2 | |
| SCHEMBL5265818 | 0.77 | MEN1 (0.57) | MEN1KMT2AKIF11SCN9AKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873069-A | Peptide amide compound, pharmaceutically acceptable salt and stereoisomer thereof, and application thereof | 天地恒一制药股份有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115707712-A | Peptide amide compound, pharmaceutically acceptable salt and stereoisomer thereof, and application thereof | 天地恒一制药股份有限公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-114728962-A | Plasma kallikrein inhibitors and uses thereof | 武田药品工业有限公司 | 2022-07-08 | — | — | CN | disclosed |