SCHEMBL23518992

SCHEMBL23518992

O=C(O)C(F)(F)Oc1ccc(OC(F)(F)F)c(F)c1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.54
SLC7A5 Q01650 1/20 0.47
PDE2A O00408 1/20 0.43
FFAR4 Q5NUL3 6/20 0.40
FFAR1 O14842 3/20 0.40
PIM1 P11309 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
PPARD Q03181 1/20 0.39
PPARA Q07869 1/20 0.39
NOTUM Q6P988 1/20 0.39
SCN9A Q15858 2/20 0.38
ABL1 P00519 1/20 0.38
SCN8A Q9UQD0 1/20 0.37
SCN10A Q9Y5Y9 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23519097 0.82 CES2 (0.41) FFAR4FFAR1PIM1PPARANOTUM
SCHEMBL23519065 0.80 EPHX2 (0.55) EPHX2PIM1MRGPRX4NOTUM
SCHEMBL19556095 0.80 PPARD (0.52) EPHX2SLC7A5FFAR4FFAR1PPARD
SCHEMBL30112070 0.80 PPARD (0.52) EPHX2SLC7A5FFAR4FFAR1PPARD
SCHEMBL14596842 0.79 SLC7A5 (0.52) EPHX2SLC7A5PDE2AFFAR4FFAR1
SCHEMBL28958691 0.79 EPHX2 (0.53) EPHX2SLC7A5PDE2APIM1SCN9A
SCHEMBL23519082 0.78 PPARA (0.48) FFAR4FFAR1MRGPRX4PPARA
SCHEMBL17186832 0.77 EPHX2 (0.46) EPHX2NOTUMSCN8ASCN10A
SCHEMBL29795192 0.77 EPHX2 (0.46) EPHX2NOTUMSCN8ASCN10A
SCHEMBL23519071 0.77 NOTUM (0.47) FFAR1PIM1MRGPRX4NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210179554-A1 ONIUM SALT COMPOUND, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210179554-A1 ONIUM SALT COMPOUND, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SLC6A5, LIFR, SLC6A9 EPHX2 3804/4885SLC7A5 122/4885PDE2A 4233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.