Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | LIPE | Q05469 | 2/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15355311 | 0.88 | SMN1; SMN2 (0.59) | GAALIPENOTUMKMT2ASMN1; SMN2 | |
| SCHEMBL29589853 | 0.88 | SMN1; SMN2 (0.59) | GAALIPENOTUMKMT2ASMN1; SMN2 | |
| SCHEMBL28475041 | 0.86 | ROCK1 (0.53) | GAAROCK2ROCK1LIPENOTUM | |
| SCHEMBL28474192 | 0.86 | ALOX15 (0.56) | ROCK2ROCK1LIPENOTUMKMT2A | |
| SCHEMBL19675154 | 0.86 | ROCK1 (0.53) | GAAROCK2ROCK1MGLLLIPE | |
| SCHEMBL29029885 | 0.86 | CYP1A2 (0.58) | GAAROCK2ROCK1LIPENOTUM | |
| SCHEMBL15878542 | 0.86 | TDP1 (0.55) | GAAROCK2ROCK1LIPENOTUM | |
| SCHEMBL19616370 | 0.85 | GAA (0.56) | GAAMGLLKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL12501430 | 0.84 | NR1H2 (0.48) | GAAROCK2ROCK1MGLLLIPE | |
| SCHEMBL15879102 | 0.83 | ROCK1 (0.51) | GAAROCK2ROCK1LIPENOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115873069-A | Peptide amide compound, pharmaceutically acceptable salt and stereoisomer thereof, and application thereof | 天地恒一制药股份有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-115707712-A | Peptide amide compound, pharmaceutically acceptable salt and stereoisomer thereof, and application thereof | 天地恒一制药股份有限公司 | 2023-02-21 | — | — | CN | disclosed |