Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 15/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.48 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | ITGAL | P20701 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23455361 | 0.93 | ITGB1 (0.57) | ITGB1ITGA5ITGA4ITGB2ICAM1 | |
| SCHEMBL23455360 | 0.93 | ITGB1 (0.57) | ITGB1ITGA5ITGA4ITGB2ICAM1 | |
| SCHEMBL30000959 | 0.93 | ITGB1 (0.57) | ITGB1ITGA5ITGA4ITGB2ICAM1 | |
| SCHEMBL30001297 | 0.91 | ITGB1 (0.44) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23455557 | 0.91 | ITGB1 (0.44) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23455558 | 0.91 | ITGB1 (0.44) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23518390 | 0.86 | ITGB1 (0.57) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23455464 | 0.86 | ITGB1 (0.59) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23455460 | 0.86 | ITGB1 (0.59) | ITGB1ITGA5ITGA4ITGB7ITGA2 | |
| SCHEMBL23455482 | 0.84 | ITGB1 (0.49) | ITGB1ITGA5ITGA4ITGAVGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115348861-A | Alpha-5 beta-1 inhibitors | 加利福尼亚大学董事会 | 2022-11-15 | — | — | CN | disclosed |