Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13510002 | 0.94 | HPGD (0.59) | HPGDRAB9ALMNAACKR3AVPR1B | |
| SCHEMBL7687826 | 0.89 | HPGD (0.62) | HPGDRAB9ALMNAACKR3ALDH1A1 | |
| SCHEMBL10864066 | 0.83 | HPGD (0.55) | HPGDRAB9ALMNAACKR3ALDH1A1 | |
| SCHEMBL12608407 | 0.83 | HPGD (0.65) | HPGDRAB9ALMNAALDH1A1NPC1 | |
| SCHEMBL28958749 | 0.82 | HDAC1 (0.47) | RAB9ALMNAALDH1A1NPC1MAPT | |
| SCHEMBL27482174 | 0.81 | LMNA (0.58) | HPGDRAB9ALMNAALDH1A1NPC1 | |
| SCHEMBL27629615 | 0.80 | LMNA (0.59) | HPGDRAB9ALMNAALDH1A1NPC1 | |
| SCHEMBL30444573 | 0.80 | EPHX2 (0.61) | HPGDRAB9ALMNAALDH1A1NPC1 | |
| SCHEMBL28958764 | 0.78 | HPGD (0.58) | HPGDRAB9ALMNAACKR3ALDH1A1 | |
| SCHEMBL7693035 | 0.78 | LMNA (0.61) | HPGDRAB9ALMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264901-B | Amino phenol oxygroup zinc complex containing 2-substituted thiazole-4-group and preparation method and application thereof | 华东理工大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-113264901-A | Amino phenol oxygroup zinc complex containing 2-substituted thiazole-4-group and preparation method and application thereof | 华东理工大学 | 2021-08-17 | — | — | CN | disclosed |