Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12667263 | 0.76 | HRH1 (0.41) | HRH1 | |
| SCHEMBL28958745 | 0.73 | HPGD (0.56) | HRH4HRH3LMNAACKR3ALDH1A1 | |
| SCHEMBL28958749 | 0.71 | HDAC1 (0.47) | HRH4HRH3LMNACYP1A2CYP2D6 | |
| SCHEMBL517979 | 0.69 | KCNH2 (0.58) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL15199526 | 0.66 | HRH1 (0.41) | HRH1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL1951197 | 0.66 | HRH4 (0.42) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL1953294 | 0.66 | HRH4 (0.42) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL1953949 | 0.66 | HRH4 (0.42) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL10748421 | 0.62 | HRH4 (0.84) | HRH4HRH3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL9637156 | 0.62 | HRH4 (0.84) | HRH4HRH3LMNASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264901-B | Amino phenol oxygroup zinc complex containing 2-substituted thiazole-4-group and preparation method and application thereof | 华东理工大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-113264901-A | Amino phenol oxygroup zinc complex containing 2-substituted thiazole-4-group and preparation method and application thereof | 华东理工大学 | 2021-08-17 | — | — | CN | disclosed |