SCHEMBL28958978

SCHEMBL28958978

Cc1ccc(C(CCC(=O)O)=NO)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
PPARG P37231 1/20 0.51
PPARA Q07869 1/20 0.51
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 2/20 0.46
RAB9A P51151 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 2/20 0.43
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43
CTBP2 P56545 1/20 0.43
POLB P06746 1/20 0.43
NPC1 O15118 1/20 0.43
GAA P10253 1/20 0.43
SRD5A2 P31213 1/20 0.42
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
ALOX12 P18054 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28958977 1.00 KMT2A (0.61) KMT2APPARGPPARAALDH1A1SMN1; SMN2
SCHEMBL7764810 0.95 KMT2A (0.56) KMT2APPARGPPARAALDH1A1SMN1; SMN2
SCHEMBL7764807 0.95 KMT2A (0.56) KMT2APPARGPPARAALDH1A1SMN1; SMN2
SCHEMBL6930112 0.87 NPC1 (0.61) KMT2ASMN1; SMN2MEN1RAB9AL3MBTL1
SCHEMBL6930113 0.87 NPC1 (0.61) KMT2ASMN1; SMN2MEN1RAB9AL3MBTL1
SCHEMBL5099030 0.82 NR4A2 (0.57) KMT2APPARGPPARAALDH1A1SMN1; SMN2
SCHEMBL6157413 0.82 NR4A2 (0.57) KMT2APPARGPPARAALDH1A1SMN1; SMN2
SCHEMBL5099035 0.82 NR4A2 (0.57) KMT2APPARGPPARAALDH1A1SMN1; SMN2
SCHEMBL28120571 0.81 ALOX15 (0.47) KMT2AALDH1A1SMN1; SMN2MEN1L3MBTL1
SCHEMBL28121003 0.81 SMN1; SMN2 (0.58) PPARGPPARAALDH1A1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621115-B Method for synthesizing oxime compounds under photocatalysis condition 河南大学 2023-05-23 CN disclosed
CN-114621115-A Method for synthesizing oxime compound under photocatalysis condition 河南大学 2022-06-14 CN disclosed