Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22906672 | 0.98 | L3MBTL1 (0.51) | L3MBTL1PRMT5WDR77JAK2JAK1 | |
| SCHEMBL20129209 | 0.98 | L3MBTL1 (0.47) | L3MBTL1PRMT5WDR77JAK2JAK1 | |
| SCHEMBL20132906 | 0.97 | L3MBTL1 (0.47) | L3MBTL1PRMT5WDR77JAK2JAK1 | |
| SCHEMBL2387673 | 0.93 | PRMT5 (0.47) | L3MBTL1PRMT5WDR77JAK2JAK1 | |
| SCHEMBL13096781 | 0.90 | STS (0.52) | L3MBTL1PRMT5WDR77JAK2JAK1 | |
| SCHEMBL20132907 | 0.89 | PRMT5 (0.45) | L3MBTL1PRMT5WDR77JAK2JAK1 | |
| SCHEMBL20133355 | 0.89 | STS (0.51) | L3MBTL1PRMT5WDR77JAK2JAK1 | |
| SCHEMBL30750608 | 0.88 | STS (0.50) | L3MBTL1PRMT5WDR77JAK2JAK1 | |
| SCHEMBL31303428 | 0.87 | STS (0.52) | L3MBTL1PRMT5WDR77JAK2JAK1 | |
| SCHEMBL31618716 | 0.87 | PRMT5 (0.49) | L3MBTL1PRMT5WDR77JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115038704-A | Nitrogen oxide donating PDE-5 and/or PDE-6 inhibitor compounds | 日东制药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| WO-2022096930-A2 | NITROGEN OXIDE-DONATING PDE-5 AND/OR PDE-6 INHIBITOR COMPOUNDS, AND USES THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2022-05-12 | — | — | WO | disclosed |