Trifluoroacetamide

Trifluoroacetamide

SCHEMBL28959533

CC(C)CC1CCCCC1.NC(=O)C(F)(F)F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSD P07339 2/20 0.39
CTSL P07711 2/20 0.38
CTSB P07858 2/20 0.38
CTSH P09668 1/20 0.38
REN P00797 1/20 0.38
CTSK P43235 5/20 0.38
ALOX5 P09917 1/20 0.38
EPHX1 P07099 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27397635 0.78 CYP1A2 (0.40) CTSLCTSBCTSHCTSK
SCHEMBL95967 0.78 CYP1A2 (0.40) CTSLCTSBCTSHCTSK
SCHEMBL1192695 0.78 CYP1A2 (0.40) CTSLCTSBCTSHCTSK
SCHEMBL3032410 0.78 CYP1A2 (0.40) CTSLCTSBCTSHCTSK
SCHEMBL198845 0.78 CYP1A2 (0.40) CTSLCTSBCTSHCTSK
SCHEMBL7739849 0.78 CYP1A2 (0.40) CTSLCTSBCTSHCTSK
SCHEMBL9253994 0.78 CYP1A2 (0.40) CTSLCTSBCTSHCTSK
SCHEMBL7491521 0.78 CYP1A2 (0.40) CTSLCTSBCTSHCTSK
SCHEMBL198169 0.76
Formic Acid SCHEMBL29019757 0.75 CTSK (0.39) CTSDCTSLCTSBCTSHCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114630835-A Process for the preparation of peptide compounds comprising sterically bulky amino acids 中外制药株式会社 2022-06-14 CN disclosed