Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29021186 | 0.86 | EGFR (0.62) | EGFR | |
| SCHEMBL27202161 | 0.84 | EGFR (0.56) | EGFR | |
| SCHEMBL30028028 | 0.84 | EGFR (0.56) | EGFR | |
| SCHEMBL30885470 | 0.84 | EGFR (0.55) | EGFR | |
| SCHEMBL26961591 | 0.83 | EGFR (0.66) | EGFR | |
| SCHEMBL29083963 | 0.82 | EGFR (0.65) | EGFR | |
| SCHEMBL27202129 | 0.81 | EGFR (0.55) | EGFR | |
| SCHEMBL25368138 | 0.81 | EGFR (0.74) | EGFR | |
| SCHEMBL29134176 | 0.81 | EGFR (0.58) | EGFR | |
| SCHEMBL26961618 | 0.81 | EGFR (0.76) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222637-A | EGFR degrading agents and related methods of use | 百济神州有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-115260237-A | EGFR-degrading agents and related methods of use | 百济神州(北京)生物科技有限公司 | 2022-11-01 | — | — | CN | disclosed |