Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28960088 | 0.86 | EGFR (0.57) | EGFR | |
| SCHEMBL24204763 | 0.84 | EGFR (0.70) | EGFR | |
| SCHEMBL30579737 | 0.84 | EGFR (0.88) | EGFR | |
| SCHEMBL25340594 | 0.84 | EGFR (0.88) | EGFR | |
| SCHEMBL26403482 | 0.83 | EGFR (0.69) | EGFR | |
| SCHEMBL31204311 | 0.83 | EGFR (0.68) | EGFR | |
| SCHEMBL31204414 | 0.82 | EGFR (0.67) | EGFR | |
| SCHEMBL26380124 | 0.82 | EGFR (0.67) | EGFR | |
| SCHEMBL25368138 | 0.82 | EGFR (0.74) | EGFR | |
| SCHEMBL29134176 | 0.81 | EGFR (0.58) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323580-A | Conjugated degradation (EGFR) of EGFR inhibitors to E3 ligase ligands and methods of use | 百济神州有限公司 | 2023-06-23 | — | — | CN | disclosed |