Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3650526 | 0.84 | CYP1A2 (0.52) | MEN1KMT2APOLBPLECPARP1 | |
| SCHEMBL30976328 | 0.76 | MPO (0.44) | POLBMAPTLMNADAOCA1 | |
| SCHEMBL8834687 | 0.75 | KDM4E (0.53) | MEN1KMT2APOLBPLECPARP1 | |
| SCHEMBL10746329 | 0.72 | MEN1 (0.46) | MEN1KMT2AMAPTLMNACYP1A2 | |
| SCHEMBL3903296 | 0.72 | MEN1 (0.49) | MEN1KMT2APOLBPARP1MAPT | |
| SCHEMBL4064440 | 0.72 | MEN1 (0.60) | MEN1KMT2APOLBPLECPARP1 | |
| SCHEMBL895627 | 0.71 | DAO (0.73) | MEN1KMT2APARP1MAPTLMNA | |
| SCHEMBL3656241 | 0.70 | F2RL3 (0.46) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL16138106 | 0.70 | DAO (0.53) | MEN1KMT2APOLBPARP1MAPT | |
| SCHEMBL3648969 | 0.70 | MAPT (0.53) | MEN1KMT2APOLBPLECPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572282-B | Pyrazole amide compound containing aromatic heterocyclic structure, and preparation method and application thereof | 华东理工大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-115572282-A | Pyrazole amide compound containing aromatic heterocyclic structure, and preparation method and application thereof | 华东理工大学 | 2023-01-06 | — | — | CN | disclosed |