Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 7/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28961323 | 1.00 | KLK5 (0.40) | KLK5ACEALDH1A1MAPTCTSS | |
| SCHEMBL28960834 | 0.91 | ALDH1A1 (0.38) | KLK5ACEALDH1A1MAPTCTSS | |
| SCHEMBL24879919 | 0.91 | ALDH1A1 (0.38) | KLK5ACEALDH1A1MAPTCTSS | |
| SCHEMBL26645450 | 0.85 | AAK1 (0.36) | ACECTSSCTSKCTSBPPARA | |
| SCHEMBL26645447 | 0.85 | AAK1 (0.36) | ACECTSSCTSKCTSBPPARA | |
| SCHEMBL26645540 | 0.85 | AAK1 (0.36) | ACECTSSCTSKCTSBPPARA | |
| SCHEMBL26645166 | 0.77 | AAK1 (0.35) | ACECTSSCTSKCTSBAAK1 | |
| SCHEMBL26645092 | 0.77 | AAK1 (0.35) | ACECTSSCTSKCTSBAAK1 | |
| SCHEMBL26645083 | 0.77 | AAK1 (0.35) | ACECTSSCTSKCTSBAAK1 | |
| SCHEMBL30622865 | 0.76 | AAK1 (0.36) | ACECTSSCTSKCTSBAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594680-A | TEAD inhibitor | 武汉人福创新药物研发中心有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |