Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896143 | 0.86 | APEX1 (0.36) | APEX1PDK2ALDH1A1MAPTITGA4 | |
| SCHEMBL233774 | 0.86 | APEX1 (0.42) | APEX1PDK2ALDH1A1MAPTITGA4 | |
| SCHEMBL29415598 | 0.86 | APEX1 (0.42) | APEX1PDK2ALDH1A1MAPTITGA4 | |
| Lithium SCHEMBL31124519 | 0.84 | APEX1 (0.41) | APEX1PDK2ALDH1A1MAPTITGA4 | |
| SCHEMBL13136007 | 0.82 | APEX1 (0.33) | APEX1PDK2 | |
| SCHEMBL2893888 | 0.79 | APEX1 (0.42) | APEX1PDK2ALDH1A1MAPTITGA4 | |
| SCHEMBL20201326 | 0.76 | APEX1 (0.47) | APEX1PDK2ALDH1A1MAPTITGA4 | |
| SCHEMBL5082827 | 0.76 | APEX1 (0.36) | APEX1PDK2ALDH1A1MAPTITGA4 | |
| SCHEMBL5078674 | 0.75 | APEX1 (0.35) | APEX1PDK2ALDH1A1MAPTITGA4 | |
| SCHEMBL5323211 | 0.74 | APEX1 (0.41) | APEX1PDK2ALDH1A1MAPTITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614162-B2 | Catalyst composition with phosphorus-based donor and method | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-24 | — | — | US | disclosed |
| US-20130102457-A1 | Catalyst Composition with Phosphorus-Based Donor and Method | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-25 | — | — | US | disclosed |
| US-20100227988-A1 | Catalyst Composition with Phosphorus-Based Donor and Method | DOW GLOBAL TECHNOLOGIES LLC | 2010-09-09 | — | — | US | disclosed |