SCHEMBL5082827

SCHEMBL5082827

CCOCC1(COC)c2ccccc2-c2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.36
PDK2 Q15119 10/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
ITGA4 P13612 1/20 0.32
HSD11B1 P28845 1/20 0.32
CYP2D6 P10635 1/20 0.31
PGR P06401 1/20 0.31
APP P05067 1/20 0.30
KCNQ2 O43526 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6437219 0.93 APEX1 (0.40) APEX1PDK2SMN1; SMN2CYP2D6PGR
SCHEMBL29757337 0.93 APEX1 (0.40) APEX1PDK2SMN1; SMN2CYP2D6PGR
SCHEMBL233774 0.89 APEX1 (0.42) APEX1PDK2SMN1; SMN2ALDH1A1MAPT
SCHEMBL29415598 0.89 APEX1 (0.42) APEX1PDK2SMN1; SMN2ALDH1A1MAPT
Lithium SCHEMBL31124519 0.87 APEX1 (0.41) APEX1PDK2SMN1; SMN2ALDH1A1MAPT
SCHEMBL5080025 0.82 PDK2 (0.41) APEX1PDK2ALDH1A1CYP3A4CYP2C9
SCHEMBL5082309 0.82 APEX1 (0.40) APEX1PDK2SMN1; SMN2ALDH1A1MAPT
SCHEMBL13136007 0.81 APEX1 (0.33) APEX1PDK2SMN1; SMN2
SCHEMBL5078695 0.81 SMN1; SMN2 (0.34) APEX1PDK2SMN1; SMN2HSD11B1KCNQ2
SCHEMBL5084616 0.80 APEX1 (0.33) APEX1PDK2SMN1; SMN2HSD11B1KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364305-B2 Polyolefin and a process for preparing the same RELIANCE INDUSTRIES LIMITED (IN) 2019-07-30 US claimed
US-20180312615-A1 A Polyolefin And A Process For Preparing The Same RELIANCE INDUSTRIES LIMITED (IN) 2018-11-01 US claimed
US-20170121430-A1 Ziegler-Natta Catalyst Composition And A Process For Its Preparation RELIANCE INDUSTRIES LIMITED (IN) 2017-05-04 US claimed
WO-2015177732-A1 A ZIEGLER-NATTA CATALYST COMPOSITION AND A PROCESS FOR ITS PREPARATION RELIANCE INDUSTRIES LIMITED (IN) 2015-11-26 WO claimed
EP-1260523-B1 CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS CHINA PETROCHEMICAL CORP (CN) 2013-01-23 EP claimed
US-7049377-B1 1,3-diethers and components and catalysts for the polymerization of olefins, containing said diethers BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2006-05-23 US claimed
US-7022640-B2 1,3-diethers and components and catalysts for the polymerization of olefins, containing said diethers BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2006-04-04 US claimed
US-20040235645-A1 1,3-Diethers and components and catalysts for the polymerization of olefins, containing said diethers MORINI GIAMPIERO (IT) 2004-11-25 US claimed
CN-1473809-A Diethers suitable for use in the preparation of ziegler-natta catalysts ��������ϩ����������޹�˾ 2004-02-11 CN claimed
US-6683017-B2 SOLID CATALYST COMPONENT COMPRISING TITANIUM, MAGNESIUM, HALOGEN AND A 1,3-DIETHER, ORGANIC ALUMINUM COMPOUND, ORGANIC SILICON COMPOUND CHINA PETRO - CHEMICAL CORPORATION (CN) 2004-01-27 US claimed
EP-1260523-A1 CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS CHINA PETROCHEMICAL CORPORATION (CN) 2002-11-27 EP claimed
US-20010025006-A1 Catalyst system for the (co) polymerization of olefins BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, SINOPEC (CN) 2001-09-27 US claimed
EP-0728769-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1998-08-19 EP claimed
CN-1141285-A Diethers suitable for use in the preparation of ziegler-natta catalysts MONTELL NORTH AMERICA INC (US) 1997-01-29 CN claimed
EP-0728724-A1 Diethers suitable for use in the preparation of Ziegler-Natta catalysts MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP claimed
EP-0728769-A1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP claimed
US-10954324-B2 Catalyst component for high activity and high stereoselectivity in olefin polymerization FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2021-03-23 US disclosed
US-10364305-B2 Polyolefin and a process for preparing the same RELIANCE INDUSTRIES LIMITED (IN) 2019-07-30 US disclosed
EP-0728770-A1 Process for the preparation of solid catalyst components for the polymerization of olefins MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP disclosed
EP-0728724-A1 Diethers suitable for use in the preparation of Ziegler-Natta catalysts MONTELL NORTH AMERICA INC. (US) 1996-08-28 EP disclosed