Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 14/20 | 0.77 |
| ▸ | NLRP3 | Q96P20 | 10/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30040866 | 1.00 | IL1B (0.77) | IL1BNLRP3 | |
| SCHEMBL28961912 | 1.00 | IL1B (0.77) | IL1BNLRP3 | |
| SCHEMBL28934457 | 0.96 | IL1B (0.74) | IL1BNLRP3 | |
| SCHEMBL28934453 | 0.96 | IL1B (0.74) | IL1BNLRP3 | |
| SCHEMBL28965250 | 0.96 | IL1B (0.77) | IL1BNLRP3 | |
| SCHEMBL30108827 | 0.96 | IL1B (0.74) | IL1BNLRP3 | |
| SCHEMBL28965247 | 0.96 | IL1B (0.77) | IL1BNLRP3 | |
| SCHEMBL28961832 | 0.94 | IL1B (0.79) | IL1BNLRP3 | |
| SCHEMBL28961837 | 0.94 | IL1B (0.79) | IL1BNLRP3 | |
| SCHEMBL26438736 | 0.91 | IL1B (0.74) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417856-A | Pharmaceutical application of substituted heteroaraliphthalazine derivatives and preparation method thereof | 成都奥睿药业有限公司 | 2022-12-02 | — | — | CN | disclosed |