Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299124 | 0.88 | KDM4E (0.63) | KDM4EMAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL298505 | 0.80 | KDM4E (0.46) | KDM4EMAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL890218 | 0.78 | NPC1 (0.50) | KDM4EMAPTRAB9AMEN1KMT2A | |
| SCHEMBL16785690 | 0.76 | DPP4 (0.53) | KDM4EMAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL14437828 | 0.76 | DPP4 (0.53) | KDM4EMAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL16785691 | 0.76 | DPP4 (0.53) | KDM4EMAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL16785692 | 0.76 | DPP4 (0.53) | KDM4EMAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL16785688 | 0.76 | DPP4 (0.53) | KDM4EMAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL498537 | 0.76 | DPP4 (0.53) | KDM4EMAPTRAB9AL3MBTL1MEN1 | |
| SCHEMBL23611278 | 0.75 | DPP4 (0.65) | KDM4EMAPTRAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |