SCHEMBL498537

SCHEMBL498537

Cc1ccc(-c2ccc(-c3cccs3)s2)s1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.53
ALDH1A1 P00352 7/20 0.52
KDM4E B2RXH2 6/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
MAPT P10636 3/20 0.52
LMNA P02545 2/20 0.52
GAA P10253 2/20 0.52
GLA P06280 1/20 0.52
LTA4H P09960 1/20 0.50
NPC1 O15118 4/20 0.46
RAB9A P51151 3/20 0.46
HSD17B10 Q99714 3/20 0.46
MEN1 O00255 2/20 0.46
HPGD P15428 2/20 0.46
KMT2A Q03164 2/20 0.46
TP53 P04637 1/20 0.46
POLB P06746 1/20 0.46
NFKB1 P19838 1/20 0.46
MAPK1 P28482 1/20 0.46
CASP1 P29466 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16785691 1.00 DPP4 (0.53) DPP4ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL16785688 1.00 DPP4 (0.53) DPP4ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL16785690 1.00 DPP4 (0.53) DPP4ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL14437828 1.00 DPP4 (0.53) DPP4ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL16785692 1.00 DPP4 (0.53) DPP4ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL144406 0.98 ALDH1A1 (0.53) DPP4ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL13144214 0.91 DPP4 (0.46) DPP4ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL23611278 0.86 DPP4 (0.65) DPP4ALDH1A1KDM4EL3MBTL1MAPT
SCHEMBL13707354 0.86 DPP4 (0.65) DPP4ALDH1A1KDM4EL3MBTL1MAPT
Alpha-Terthienyl SCHEMBL147274 0.86 DPP4 (0.65) DPP4ALDH1A1KDM4EL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240229026-A1 CHIRAL CONTROL WAVE LIFE SCIENCES LTD. (SG) 2024-07-11 US disclosed
WO-2023210569-A1 NOVEL COMPOUND, CONJUGATED POLYMER AND METHOD FOR PRODUCING SAME, FILM FORMATION COMPOSITION, ORGANIC THIN FILM, AND ORGANIC SEMICONDUCTOR ELEMENT 東ソー株式会社 2023-11-02 WO disclosed
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US disclosed
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US disclosed
US-20230302038-A1 RNAS FOR COMPLEMENT INHIBITION SIXTH STREET LENDING PARTNERS 2023-09-28 US disclosed
EP-2764034-B1 POLYMERS BASED ON BENZODIONES CLAP CO LTD (KR) 2023-08-30 EP disclosed
WO-2022148752-A9 PHOTOCHROMIC DYES AND POLYMERIC MATRIX FOR AN EFFICIENT DIMMING FILM Sony Group Corporation (JP) 2023-08-03 WO disclosed
EP-4219516-A2 CHIRAL CONTROL Wave Life Sciences Ltd. (SG) 2023-08-02 EP disclosed
US-20230212606-A1 COMPOSITIONS AND METHODS FOR TREATING KCNQ4-ASSOCIATED HEARING LOSS AKOUOS, INC. 2023-07-06 US disclosed
WO-2023129496-A2 RNAS FOR COMPLEMENT INHIBITION APELLIS PHARMACEUTICALS, INC. (US) 2023-07-06 WO disclosed
WO-2001085213-A2 SUPPORTS FOR PHOTOSENSITIZER FORMULATIONS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2001-11-15 WO disclosed
WO-2001035996-A2 USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA QLT INC. (CA) 2001-05-25 WO disclosed
WO-2001035997-A2 USE OF LOW-DOSE PDT TO INHIBIT RESTENOSIS QLT INC. (CA) 2001-05-25 WO disclosed
US-5912473-A Method of manufacturing organic oriented film and method of manufacturing electronic device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-06-15 US disclosed
US-5753692-A PLANT EXTRACTS, IMMUNOSTIMULANTS TREATING IMMUNODEFICIENCY DISEASES INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-19 US disclosed
US-5747525-A ANTITUMOR AGENTS OF OLIGOMERS OF THIOPHENE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-05 US disclosed
US-5602170-A ADMINISTERING ANTIIFLAMMATORY AGENT INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1997-02-11 US disclosed
US-5546889-A Method of manufacturing organic oriented film and method of manufacturing electronic device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1996-08-20 US disclosed
US-5180838-A Terthienyl compounds as insecticides HER MAJESTY THE QUEEN AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENSE OF HER MAJESTY'S CANADIAN GOVERNMENT (CA) 1993-01-19 US disclosed
US-5045563-A Terthienyl Compound HER MAJESTY THE QUEEN IN RIGHT OF CANADA, AS REPRESENTED BY MINISTER OF NATIONAL DEFENCE OF HER MAJESTY'S CANADIAN GOVERNMENT (CA) 1991-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212606-A1 COMPOSITIONS AND METHODS FOR TREATING KCNQ4-ASSOCIATED HEARING LOSS KCNQ4, KCNQ1, KCNJ4 DPP4 1361/4885ALDH1A1 4447/4885KDM4E 885/4885
US-20240229026-A1 CHIRAL CONTROL RNGTT, POLI, NSUN3 DPP4 2127/4885ALDH1A1 2867/4885KDM4E 3578/4885
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION POLRMT, DCLRE1B, RNGTT DPP4 1041/4885ALDH1A1 3318/4885KDM4E 3297/4885
US-20230302038-A1 RNAS FOR COMPLEMENT INHIBITION SNRPE, RNASE1, SNRPF DPP4 3492/4885ALDH1A1 4397/4885KDM4E 3867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.