SCHEMBL28964409

SCHEMBL28964409

FC(F)(F)c1ccc(-c2ccccn2)cc1.[Pt]

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.64
TGFBR1 P36897 1/20 0.55
KIF11 P52732 2/20 0.52
TOP1 P11387 2/20 0.50
GRM5 P41594 1/20 0.50
NPY5R Q15761 1/20 0.49
CYP1A2 P05177 2/20 0.48
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
POLB P06746 1/20 0.48
CCR1 P32246 1/20 0.48
CCR5 P51681 1/20 0.48
CCR8 P51685 1/20 0.48
METAP1 P53582 1/20 0.48
BLM P54132 1/20 0.48
HIF1A Q16665 1/20 0.48
DOHH Q9BU89 1/20 0.48
P4HTM Q9NXG6 1/20 0.48
CBFB Q13951 1/20 0.48
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2615556 0.98 TRPV1 (0.66) TRPV1TGFBR1KIF11TOP1GRM5
SCHEMBL30007927 0.98 TRPV1 (0.66) TRPV1TGFBR1KIF11TOP1GRM5
SCHEMBL28732649 0.96 TRPV1 (0.64) TRPV1TGFBR1KIF11TOP1GRM5
SCHEMBL28234646 0.93 TRPV1 (0.61) TRPV1TGFBR1KIF11TOP1GRM5
SCHEMBL28475279 0.88 SMN1; SMN2 (0.58) TRPV1TGFBR1KIF11TOP1GRM5
SCHEMBL26547958 0.87 TRPV1 (0.56) TRPV1TGFBR1KIF11TOP1GRM5
SCHEMBL26548391 0.87 TRPV1 (0.56) TRPV1TGFBR1KIF11TOP1GRM5
SCHEMBL26548885 0.85 TRPV1 (0.54) TRPV1TGFBR1KIF11TOP1GRM5
SCHEMBL26548576 0.85 TRPV1 (0.54) TRPV1TGFBR1KIF11TOP1GRM5
SCHEMBL14073533 0.84 TRPV1 (0.53) TRPV1TGFBR1KIF11TOP1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110330534-B Novel 2-phenylpyridine-platinum (IV) precursor anticancer complex and synthesis method and application thereof 玉林师范学院 2022-06-21 CN disclosed