Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.66 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 2/20 | 0.54 |
| ▸ | TOP1 | P11387 | 2/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615556 | 1.00 | TRPV1 (0.66) | TRPV1TGFBR1KIF11TOP1GRM5 | |
| SCHEMBL28964409 | 0.98 | TRPV1 (0.64) | TRPV1TGFBR1KIF11TOP1GRM5 | |
| SCHEMBL28732649 | 0.98 | TRPV1 (0.64) | TRPV1TGFBR1KIF11TOP1GRM5 | |
| SCHEMBL28234646 | 0.94 | TRPV1 (0.61) | TRPV1TGFBR1KIF11TOP1GRM5 | |
| SCHEMBL26548391 | 0.88 | TRPV1 (0.56) | TRPV1TGFBR1KIF11TOP1GRM5 | |
| SCHEMBL26547958 | 0.88 | TRPV1 (0.56) | TRPV1TGFBR1KIF11TOP1GRM5 | |
| SCHEMBL26548576 | 0.87 | TRPV1 (0.54) | TRPV1TGFBR1KIF11TOP1GRM5 | |
| SCHEMBL26548885 | 0.87 | TRPV1 (0.54) | TRPV1TGFBR1KIF11TOP1GRM5 | |
| SCHEMBL28475279 | 0.86 | SMN1; SMN2 (0.58) | TRPV1TGFBR1KIF11TOP1GRM5 | |
| SCHEMBL14073533 | 0.86 | TRPV1 (0.53) | TRPV1TGFBR1KIF11TOP1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220401461-A1 | Pharmaceutical Composition for Protecting Cartilage | KYOTO UNIVERSITY (JP) | 2022-12-22 | — | — | US | disclosed |
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220401461-A1 | Pharmaceutical Composition for Protecting Cartilage | COL2A1, MATR3, COL1A1 | TRPV1 721/4885TGFBR1 2026/4885KIF11 1764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.