Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28964452 | 1.00 | ADORA2A (0.56) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL453952 | 0.92 | ADORA2A (0.57) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL29421357 | 0.92 | ADORA2A (0.57) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL453954 | 0.92 | ADORA2A (0.57) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL453953 | 0.92 | ADORA2A (0.57) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL29047905 | 0.92 | ADORA2A (0.60) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL29047902 | 0.92 | ADORA2A (0.60) | ADORA2AADORA2BTP53CYP3A4TSHR | |
| SCHEMBL28659434 | 0.90 | SLC29A1 (0.58) | TP53CYP3A4TSHRALOX12NFKB1 | |
| SCHEMBL28659436 | 0.90 | SLC29A1 (0.58) | TP53CYP3A4TSHRALOX12NFKB1 | |
| SCHEMBL3692894 | 0.88 | PRMT5 (0.60) | ADORA2AADORA2BTP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768438-A | Lipid nanoparticles for delivery of therapeutic agents to the lung | 盖纳万科学有限公司 | 2023-03-07 | — | — | CN | disclosed |