SCHEMBL29047902

SCHEMBL29047902

C[C@@H](O)[C@H](N)C(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.69

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.60
ADORA2B P29275 1/20 0.60
TP53 P04637 1/20 0.60
CYP3A4 P08684 1/20 0.60
TSHR P16473 1/20 0.60
ALOX12 P18054 1/20 0.60
NFKB1 P19838 1/20 0.60
HIF1A Q16665 1/20 0.60
ALDH1A1 P00352 1/20 0.60
HPGD P15428 1/20 0.60
PMP22 Q01453 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29047905 1.00 ADORA2A (0.60) ADORA2AADORA2BTP53CYP3A4TSHR
SCHEMBL453952 0.93 ADORA2A (0.57) ADORA2AADORA2BTP53CYP3A4TSHR
SCHEMBL29421357 0.93 ADORA2A (0.57) ADORA2AADORA2BTP53CYP3A4TSHR
SCHEMBL453953 0.93 ADORA2A (0.57) ADORA2AADORA2BTP53CYP3A4TSHR
SCHEMBL453954 0.93 ADORA2A (0.57) ADORA2AADORA2BTP53CYP3A4TSHR
SCHEMBL2480941 0.92 ADORA2A (0.62) ADORA2AADORA2BTP53CYP3A4TSHR
SCHEMBL28964452 0.92 ADORA2A (0.56) ADORA2AADORA2BTP53CYP3A4TSHR
SCHEMBL28964455 0.92 ADORA2A (0.56) ADORA2AADORA2BTP53CYP3A4TSHR
SCHEMBL3692894 0.92 PRMT5 (0.60) ADORA2AADORA2BTP53CYP3A4TSHR
SCHEMBL28659436 0.91 SLC29A1 (0.58) TP53CYP3A4TSHRALOX12NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768533-A Improved method for in vitro transcription 阿克丘勒斯治疗公司 2025-04-04 CN disclosed
CN-118900701-A Poly (alkyl oxazoline) -lipid conjugates and compositions containing poly (alkyl oxazoline) lipid particles of (alkyl oxazoline) -lipid conjugates 盖纳万科学有限公司 2024-11-05 CN disclosed
CN-118786215-A Analysis of RNA molecules using catalytic nucleic acids 生物技术欧洲股份公司 2024-10-15 CN disclosed
CN-118613500-A Modified mRNA treatment 沙塔克实验室有限公司 2024-09-06 CN disclosed
CN-118103516-A Modified replicable RNAs and related compositions and uses thereof 生物技术欧洲股份公司 2024-05-28 CN disclosed
CN-118019846-A Compositions comprising CRISPR nucleases and uses thereof 阿伯生物技术公司 2024-05-10 CN disclosed
CN-117940158-A Novel lipid nanoparticles comprising phosphatidylserine for nucleic acid delivery 库瑞瓦格欧洲公司 2024-04-26 CN disclosed
CN-117940118-A Novel lipid nanoparticles for nucleic acid delivery 库瑞瓦格欧洲公司 2024-04-26 CN disclosed
CN-117897485-A RNA-guided gene editing system comprising a target hydroxy acid oxidase 1 (HAO 1) and uses thereof 阿伯生物技术公司 2024-04-16 CN disclosed
CN-117813379-A Gene editing system comprising CRISPR nucleases and uses thereof 阿伯生物技术公司 2024-04-02 CN disclosed
CN-117295816-A Compositions comprising variant polypeptides and uses thereof 阿伯生物技术公司 2023-12-26 CN disclosed
CN-117136233-A Compositions comprising variant Cas12i4 polypeptides and uses thereof 阿伯生物技术公司 2023-11-28 CN disclosed
CN-117043326-A Compositions comprising variant polypeptides and uses thereof 阿伯生物技术公司 2023-11-10 CN disclosed
CN-116867898-A Compositions comprising TRAC-targeted RNA guides and uses thereof 阿伯生物技术公司 2023-10-10 CN disclosed
CN-116648505-A Compositions comprising B2M-targeted RNA guides and uses thereof 阿伯生物技术公司 2023-08-25 CN disclosed
CN-116601292-A Compositions comprising RNA guides targeting BCL11A and uses thereof 阿伯生物技术公司 2023-08-15 CN disclosed
CN-116157520-A Compositions and methods for genome editing 塑造治疗公司 2023-05-23 CN disclosed
CN-116134020-A Lipid compounds comprising at least one terminal group of formula-NH-CX-A or-NH-CX-NH-A, compositions containing them and uses thereof 赛诺菲巴斯德有限公司 2023-05-16 CN disclosed
CN-116064623-A Method for increasing replication of circular DNA molecules 库瑞瓦格制造业有限公司 2023-05-05 CN disclosed
CN-115361954-A Compositions for translation and methods of use thereof 旗舰创业创新第六有限责任公司 2022-11-18 CN disclosed