Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | CLPP | Q16740 | 3/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28965703 | 0.83 | HRH3 (0.37) | HRH3CFTRHRH1BRS3CLPP | |
| SCHEMBL30351023 | 0.83 | HRH3 (0.37) | HRH3CFTRHRH1BRS3CLPP | |
| SCHEMBL30351021 | 0.83 | HRH3 (0.37) | HRH3CFTRHRH1BRS3CLPP | |
| SCHEMBL9923777 | 0.78 | C5AR1 (0.32) | HTR2AHTR2CHTR2BDRD2DRD4 | |
| SCHEMBL30767848 | 0.73 | KMT2A (0.53) | CLPPC5AR1 | |
| SCHEMBL322777 | 0.73 | KMT2A (0.53) | CLPPC5AR1 | |
| SCHEMBL4987983 | 0.72 | BRS3 (0.41) | HRH3CFTRHRH1BRS3FAAH | |
| SCHEMBL855182 | 0.72 | HTR2A (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL28965783 | 0.71 | P2RX3 (0.37) | HRH3CFTRCLPPC5AR1 | |
| SCHEMBL4982554 | 0.71 | BRS3 (0.42) | HRH3CFTRHRH1BRS3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115626922-A | 5,6,7,8-tetrahydropyrido [4,3-d ] pyrimidin-4-ol derivatives and uses thereof | 苏州恩华生物医药科技有限公司 | 2023-01-20 | — | — | CN | disclosed |