SCHEMBL28965792

SCHEMBL28965792

O=C(/C=C/c1ccc(O)cc1)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 7/20 0.67
PPARG P37231 1/20 0.66
NOS3 P29474 4/20 0.57
NOS1 P29475 4/20 0.57
GRIA1 P42261 1/20 0.55
FOLH1 Q04609 1/20 0.53
NAALAD2 Q9Y3Q0 1/20 0.53
XDH P47989 1/20 0.53
MMP1 P03956 2/20 0.52
MMP2 P08253 2/20 0.52
MMP9 P14780 2/20 0.52
PTPN2 P17706 2/20 0.52
PTPN1 P18031 2/20 0.52
CDC25B P30305 2/20 0.52
PTPN6 P29350 1/20 0.52
AKR1B10 O60218 1/20 0.50
AKR1B1 P15121 1/20 0.50
MAOB P27338 1/20 0.50
PTGS2 P35354 1/20 0.50
GLO1 Q04760 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1711585 1.00 NOS2 (0.67) NOS2PPARGNOS3NOS1GRIA1
SCHEMBL3168224 1.00 NOS2 (0.67) NOS2PPARGNOS3NOS1GRIA1
SCHEMBL28965832 1.00 NOS2 (0.67) NOS2PPARGNOS3NOS1GRIA1
SCHEMBL1558521 0.94 NOS2 (0.75) NOS2PPARGNOS3NOS1GRIA1
SCHEMBL1558519 0.94 NOS2 (0.75) NOS2PPARGNOS3NOS1GRIA1
SCHEMBL1558517 0.94 NOS2 (0.75) NOS2PPARGNOS3NOS1GRIA1
SCHEMBL21996040 0.94 NOS2 (0.75) NOS2PPARGNOS3NOS1GRIA1
SCHEMBL21996042 0.94 NOS2 (0.75) NOS2PPARGNOS3NOS1GRIA1
SCHEMBL21996039 0.94 NOS2 (0.75) NOS2PPARGNOS3NOS1GRIA1
SCHEMBL10703001 0.94 NOS2 (0.60) NOS2PPARGNOS3NOS1GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114645037-A Means and methods for detoxification of ochratoxin A 艾尔柏股份公司 2022-06-21 CN disclosed