Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143541 | 0.75 | ALDH1A1 (0.59) | NOX1FFAR1FFAR4EGFRMAOB | |
| SCHEMBL9235297 | 0.74 | MAOB (0.61) | NOX1FFAR1FFAR4EGFRMAOB | |
| Benzyloxyphenylpropanoic Acid SCHEMBL1134648 | 0.73 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL1172055 | 0.73 | FFAR1 (0.71) | FFAR1FFAR4MAOBALOX5NR4A1 | |
| SCHEMBL1744939 | 0.73 | FFAR1 (1.00) | FFAR1FFAR4 | |
| SCHEMBL11516765 | 0.73 | NOX1 (0.54) | NOX1EGFRMAOBLTA4HALOX5 | |
| SCHEMBL14305723 | 0.73 | FFAR1 (0.91) | FFAR1FFAR4 | |
| SCHEMBL10789083 | 0.72 | EGFR (1.00) | EGFRMAOBLTA4HALOX5ALDH1A1 | |
| Benzyloxyphenylpropanoic Acid SCHEMBL30117578 | 0.72 | FFAR1 (0.97) | FFAR1FFAR4 | |
| SCHEMBL1115038 | 0.72 | FFAR1 (0.69) | FFAR1FFAR4ALOX5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BioLab Corporation (JP) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128685-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2010-11-11 | — | — | WO | disclosed |