Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 11/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28966679 | 1.00 | MAP4K4 (0.52) | MAP4K4HDAC1CHRM2CHRM1GPR119 | |
| SCHEMBL28966641 | 1.00 | MAP4K4 (0.52) | MAP4K4HDAC1CHRM2CHRM1GPR119 | |
| SCHEMBL26089377 | 0.85 | CHRM2 (0.57) | CHRM2CHRM1SLC6A9CHRM5CHRM3 | |
| SCHEMBL21460227 | 0.84 | MAP4K4 (0.54) | MAP4K4HDAC1GPR119GRM1 | |
| SCHEMBL21484275 | 0.84 | MAP4K4 (0.59) | MAP4K4HDAC1GPR119GRM1EIF2AK4 | |
| SCHEMBL23560874 | 0.84 | MAP4K4 (0.54) | MAP4K4HDAC1GPR119GRM1 | |
| SCHEMBL31105042 | 0.84 | MAP4K4 (0.54) | MAP4K4HDAC1GPR119GRM1 | |
| SCHEMBL21460229 | 0.84 | MAP4K4 (0.54) | MAP4K4HDAC1GPR119GRM1 | |
| SCHEMBL31104870 | 0.84 | MAP4K4 (0.59) | MAP4K4HDAC1GPR119GRM1EIF2AK4 | |
| SCHEMBL21483223 | 0.84 | MAP4K4 (0.59) | MAP4K4HDAC1GPR119GRM1EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745971-B | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-115745971-A | PARP7 inhibitor and application thereof | 重庆华森制药股份有限公司 | 2023-03-07 | — | — | CN | disclosed |