Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | POLB | P06746 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | ALPL | P05186 | 1/20 | 0.59 |
| ▸ | ALPI | P09923 | 1/20 | 0.59 |
| ▸ | ALPG | P10696 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897859 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2898196 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2896713 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2896709 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL13220180 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL13025036 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2898197 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2897863 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2898198 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL2897860 | 1.00 | MEN1 (0.69) | MEN1KMT2APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466177-B2 | Treating and preventing viral infections | THE UAB RESEARCH FOUNDATION (US) | 2013-06-18 | — | — | US | disclosed |
| US-20100286212-A1 | Treating and Preventing Viral Infections | THE UAB RESEARCH FOUNDATION (US) | 2010-11-11 | — | — | US | disclosed |
| EP-2217573-A1 | TREATING AND PREVENTING VIRAL INFECTIONS | The UAB Research Foundation (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009059243-A1 | TREATING AND PREVENTING VIRAL INFECTIONS | THE UAB RESEARCH FOUNDATION (US) | 2009-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286212-A1 | Treating and Preventing Viral Infections | HAVCR2, IRF3, MAVS | MEN1 3172/4885KMT2A 3809/4885POLB 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.