Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505416 | 0.78 | MAPT (0.51) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL289667 | 0.77 | JAK2 (0.49) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL288828 | 0.77 | HDAC1 (0.54) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7328943 | 0.75 | TSHR (0.50) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL288615 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29571295 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL16265070 | 0.74 | SNCA (0.49) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28757629 | 0.74 | TSHR (0.58) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7329101 | 0.73 | KDM4E (0.52) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12641002 | 0.73 | TSHR (0.51) | ALDH1A1MAPTRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |