Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833248 | 0.80 | AAK1 (0.50) | AAK1ALDH1A1SMN1; SMN2PTGER1MAPK1 | |
| SCHEMBL23833250 | 0.80 | AAK1 (0.50) | AAK1ALDH1A1SMN1; SMN2PTGER1MAPK1 | |
| SCHEMBL30193038 | 0.80 | AAK1 (0.50) | AAK1ALDH1A1SMN1; SMN2PTGER1MAPK1 | |
| SCHEMBL27015309 | 0.78 | PTGER1 (0.34) | KDM4EALDH1A1SMN1; SMN2PTGER1 | |
| SCHEMBL27146597 | 0.77 | AAK1 (0.34) | KDM4EAAK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27008149 | 0.77 | AAK1 (0.34) | KDM4EAAK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30169241 | 0.69 | AAK1 (0.47) | AAK1PTGER1 | |
| SCHEMBL23833065 | 0.69 | AAK1 (0.47) | AAK1PTGER1 | |
| SCHEMBL22526458 | 0.69 | AAK1 (0.47) | AAK1PTGER1 | |
| SCHEMBL28967220 | 0.68 | AAK1 (0.48) | AAK1ALDH1A1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115776891-A | STAT degradants and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |