Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 4/20 | 0.35 |
| ▸ | CASR | P41180 | 5/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833230 | 0.78 | MRGPRX4 (0.39) | MRGPRX4HTR1DADRB2HTR1BKDM4E | |
| SCHEMBL26205645 | 0.77 | MRGPRX4 (0.43) | MRGPRX4HTR1DHTR1BKDM4ELMNA | |
| SCHEMBL30192999 | 0.75 | AAK1 (0.48) | MRGPRX4AAK1 | |
| SCHEMBL23833134 | 0.75 | AAK1 (0.48) | MRGPRX4AAK1 | |
| SCHEMBL22526336 | 0.75 | AAK1 (0.48) | MRGPRX4AAK1 | |
| SCHEMBL23833132 | 0.75 | AAK1 (0.48) | MRGPRX4AAK1 | |
| SCHEMBL28967225 | 0.69 | ALOX15 (0.39) | — | |
| SCHEMBL26205637 | 0.67 | SMN1; SMN2 (0.37) | ADRB2KDM4ELMNACYP1A2SMN1; SMN2 | |
| SCHEMBL22525452 | 0.65 | AAK1 (0.48) | AAK1 | |
| SCHEMBL30169457 | 0.65 | AAK1 (0.48) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115776891-A | STAT degradants and uses thereof | 凯麦拉医疗公司 | 2023-03-10 | — | — | CN | disclosed |