Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.59 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200 | 0.94 | LOXL2 (0.66) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| Phosphine SCHEMBL10705044 | 0.92 | LOXL2 (0.63) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL9323725 | 0.89 | LOXL2 (0.59) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL8873885 | 0.89 | LOXL2 (0.59) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| Alcohol SCHEMBL11164959 | 0.86 | CA1 (0.67) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| Benzoic Acid SCHEMBL27984290 | 0.83 | TSHR (0.61) | LOXL2CYP4A11CA1CA2MAPT | |
| SCHEMBL131711 | 0.82 | LOXL2 (0.70) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL2894685 | 0.82 | NPC1 (0.65) | MAPTNPC1SMN1; SMN2MAPK1HPGD | |
| SCHEMBL28811753 | 0.82 | LOXL2 (0.51) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| Methyl Benzoate SCHEMBL28066697 | 0.81 | TSHR (0.70) | LOXL2CYP4A11CYP4F2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611755-B | Carboxyl/sulfonic group functionalized hyperbranched heteropolyacid polyion liquid and preparation method and application thereof | 闽江学院 | 2024-02-13 | — | — | CN | claimed |
| CN-115611755-A | Carboxyl/sulfonic group functionalized hyperbranched heteropoly acid polyion liquid and preparation method and application thereof | 闽江学院 | 2023-01-17 | — | — | CN | claimed |
| CN-115611755-B | Carboxyl/sulfonic group functionalized hyperbranched heteropolyacid polyion liquid and preparation method and application thereof | 闽江学院 | 2024-02-13 | — | — | CN | disclosed |
| CN-115611755-A | Carboxyl/sulfonic group functionalized hyperbranched heteropoly acid polyion liquid and preparation method and application thereof | 闽江学院 | 2023-01-17 | — | — | CN | disclosed |