Ethane

Ethane

SCHEMBL28967597

CC.O=[N+]([O-])c1cc([N+](=O)[O-])[nH]n1

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.39
DYRK1A Q13627 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
ALDH1A1 P00352 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
TSHR P16473 1/20 0.31
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
CYP3A4 P08684 2/20 0.31
NAMPT P43490 1/20 0.31
XDH P47989 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162091 0.96 HPGD (0.41) HPGDDYRK1ACYP1A2CYP2C9TSHR
SCHEMBL2427435 0.77
SCHEMBL2544544 0.77
Butyl Formate SCHEMBL28320805 0.76 NPC1 (0.33) ALDH1A1SMN1; SMN2KMT2AMEN1NPC1
SCHEMBL3582886 0.72
SCHEMBL10399828 0.72
SCHEMBL8023464 0.72
SCHEMBL18529294 0.72
SCHEMBL10002534 0.72
SCHEMBL4255025 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110590670-B 1,2-bis (3,5-dinitropyrazolyl) ethane compound and synthetic method thereof 西安近代化学研究所 2023-03-17 CN disclosed