⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12200985 | 0.78 | HCAR2 (0.46) | — | |
| Ethane SCHEMBL28967597 | 0.77 | HPGD (0.39) | — | |
| SCHEMBL162091 | 0.76 | HPGD (0.41) | — | |
| SCHEMBL31319635 | 0.75 | HCAR2 (0.49) | — | |
| SCHEMBL13256448 | 0.74 | CCNA2 (0.53) | — | |
| SCHEMBL8023464 | 0.74 | — | — | |
| SCHEMBL18529294 | 0.74 | — | — | |
| SCHEMBL10399828 | 0.74 | — | — | |
| SCHEMBL3582886 | 0.74 | — | — | |
| SCHEMBL31401981 | 0.74 | HCAR2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448879-B | Polynitro nitrogen-rich energy-containing compound and preparation method thereof | 北京理工大学 | 2023-12-19 | — | — | CN | claimed |
| CN-116813553-A | Selective deuterated N-methylation method of polyazaaromatic compound | 四川大学 | 2023-09-29 | — | — | CN | claimed |
| CN-114213328-B | Method for synthesizing nitroamine compound | 武汉大学 | 2023-08-29 | — | — | CN | claimed |
| CN-116178271-A | Selective N-methylation method of aza aromatic ring compound | 四川大学 | 2023-05-30 | — | — | CN | claimed |
| CN-115448879-A | Polynitro nitrogen-rich energetic compound and preparation method thereof | 北京理工大学 | 2022-12-09 | — | — | CN | claimed |
| EP-4676923-A1 | BIARYLAMIDE DERIVATIVES AND THEIR USE AS PKMYT1 INHIBITORS | Cancer Research Technology Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| EP-4665734-A1 | CYCLIN-DEPENDENT KINASE (CDK2) INHIBITORS | Novartis AG (CH) | 2025-12-24 | — | — | EP | disclosed |
| US-20250304576-A1 | IKK INHIBITORS | CANCER RESEARCH TECH LTD (GB) | 2025-10-02 | — | — | US | disclosed |
| US-20250235543-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2025-07-24 | — | — | US | disclosed |
| US-20250177396-A1 | POLO-LIKE KINASE 4 (PLK4) INHIBITORS, PHARMACEUTICAL COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF | REPARE THERAPEUTICS INC. (CA) | 2025-06-05 | — | — | US | disclosed |
| EP-4522597-A1 | IKK INHIBITORS | Cancer Research Technology Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| CN-119562945-A | IKK inhibitors | 癌症研究技术有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2011112995-A1 | IMIDAZOPYRIDINES SYK INHIBITORS | GILEAD SCIENCES, INC. (US) | 2011-09-15 | — | — | WO | disclosed |
| US-20100297725-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. | 2010-11-25 | — | — | US | disclosed |
| US-7838530-B2 | Quinazoline derivatives as antiproliferative agents | ASTRAZENECA AB (SE) | 2010-11-23 | — | — | US | disclosed |
| US-7838530-B2 | Quinazoline derivatives as antiproliferative agents | ASTRAZENECA AB (SE) | 2010-11-23 | — | — | US | disclosed |
| US-20100184087-A1 | Haptens, hapten conjugates, compositions thereof and method for their preparation and use | VENTANA MEDICAL SYSTEMS, INC. | 2010-07-22 | — | — | US | disclosed |
| WO-2008013622-A2 | FUNGICIDAL AZOCYCLIC AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-31 | — | — | WO | disclosed |
| CN-1167405-C | Keratin fibre dyeing composition containing pyrazolo-(1,5-alpha)-pyrimidine derivatives, dyeing method, pyrazolo-(1,5-alpha) pyrimidine new-type derivatives and preparation method thereof | �ź㴫 | 2004-09-22 | — | — | CN | disclosed |
| CN-1196673-A | Keratin fibre dyeing composition containing pyrazolo-(1,5-alpha)-pyrimidine derivatives, dyeing method, pyrazolo-(1,5-alpha) pyrimidine new-type derivatives and preparation method thereof | OREAL (FR) | 1998-10-21 | — | — | CN | disclosed |