Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 4/20 | 0.49 |
| ▸ | AXL | P30530 | 4/20 | 0.49 |
| ▸ | RET | P07949 | 5/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | GAK | O14976 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.44 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.44 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30880718 | 0.90 | PDGFRA (0.48) | EGFRPDGFRAMETAXLRET | |
| SCHEMBL30880492 | 0.90 | EGFR (0.45) | EGFRPDGFRAMETAXLRET | |
| SCHEMBL30050696 | 0.80 | KDR (0.61) | PDGFRAMETAXLRETKDR | |
| SCHEMBL29317818 | 0.80 | KDR (0.61) | PDGFRAMETAXLRETKDR | |
| SCHEMBL29319922 | 0.79 | KDR (0.57) | PDGFRAMETAXLRETKDR | |
| SCHEMBL28968030 | 0.79 | EGFR (0.57) | EGFRPDGFRAMETSYKKDR | |
| SCHEMBL30115310 | 0.79 | EGFR (0.57) | EGFRPDGFRAMETSYKKDR | |
| SCHEMBL30050356 | 0.78 | KDR (0.59) | PDGFRAMETAXLRETKDR | |
| SCHEMBL29317871 | 0.78 | KDR (0.59) | PDGFRAMETAXLRETKDR | |
| SCHEMBL30880729 | 0.77 | PDGFRA (0.50) | EGFRPDGFRAMETAXLRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466211-B | N-phenylquinoline-4-amine compound and application thereof | 中国人民解放军空军军医大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-115466211-A | N-phenylquinoline-4-amine compound and application thereof | 中国人民解放军空军军医大学 | 2022-12-13 | — | — | CN | disclosed |