Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.57 |
| ▸ | KDR | P35968 | 7/20 | 0.55 |
| ▸ | AURKA | O14965 | 5/20 | 0.52 |
| ▸ | MET | P08581 | 4/20 | 0.52 |
| ▸ | TEK | Q02763 | 4/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAK | O14976 | 3/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.47 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.47 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.47 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.47 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30115310 | 1.00 | EGFR (0.57) | EGFRKDRAURKAMETTEK | |
| SCHEMBL22505593 | 0.82 | EGFR (0.57) | EGFRKDRAURKBPDGFRAGAK | |
| SCHEMBL22505737 | 0.79 | KDR (0.54) | EGFRKDRAURKBPDGFRAABL1 | |
| SCHEMBL28968037 | 0.79 | EGFR (0.50) | EGFRKDRAURKAMETTEK | |
| SCHEMBL31261121 | 0.79 | EGFR (0.53) | EGFRKDRAURKAMETTEK | |
| SCHEMBL23924017 | 0.78 | PDGFRB (0.64) | KDRAURKAMETTEKAURKB | |
| SCHEMBL29535684 | 0.78 | PDGFRB (0.64) | KDRAURKAMETTEKAURKB | |
| SCHEMBL30880464 | 0.78 | GAK (0.54) | EGFRKDRAURKAMETTEK | |
| Hydrochloric Acid SCHEMBL27894607 | 0.77 | PDGFRB (0.62) | KDRAURKAMETTEKAURKB | |
| SCHEMBL30880566 | 0.77 | PDGFRA (0.51) | EGFRKDRAURKAMETTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466211-B | N-phenylquinoline-4-amine compound and application thereof | 中国人民解放军空军军医大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-115466211-A | N-phenylquinoline-4-amine compound and application thereof | 中国人民解放军空军军医大学 | 2022-12-13 | — | — | CN | disclosed |