Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19313266 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2MEN1KMT2ARAPGEF3 | |
| SCHEMBL3123874 | 0.79 | MAOB (0.53) | ESR1ESR2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16316790 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AMAOBPOLBGAA | |
| SCHEMBL28521352 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2ARAPGEF3 | |
| SCHEMBL8500193 | 0.78 | ESR1 (0.61) | ESR1ESR2MEN1KMT2AABL1 | |
| Methane SCHEMBL28034573 | 0.76 | ESR1 (0.59) | ESR1ESR2MEN1KMT2AABL1 | |
| SCHEMBL17912881 | 0.73 | MAOB (0.61) | ESR1ESR2MEN1KMT2AABL1 | |
| SCHEMBL9622898 | 0.73 | MAOB (0.61) | ESR1ESR2MEN1KMT2AABL1 | |
| SCHEMBL9939154 | 0.70 | ESR1 (0.57) | ESR1ESR2MEN1KMT2AABL1 | |
| SCHEMBL8204839 | 0.70 | ALDH1A1 (0.70) | ESR1ESR2MEN1KMT2AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240586-B | 2,3-dihydro-1H-benzo [ f ] chroman-2-amine derivatives and their preparation | 山东百极地长制药有限公司 | 2023-01-24 | — | — | CN | disclosed |