Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25021947 | 1.00 | EPHX1 (0.47) | EPHX1USP30ALDH1A1EPHX2MAPT | |
| SCHEMBL29042866 | 0.99 | EPHX1 (0.48) | EPHX1USP30ALDH1A1EPHX2MAPT | |
| SCHEMBL29042867 | 0.99 | EPHX1 (0.48) | EPHX1USP30ALDH1A1EPHX2MAPT | |
| SCHEMBL29042882 | 0.99 | EPHX1 (0.48) | EPHX1USP30ALDH1A1EPHX2MAPT | |
| SCHEMBL24033437 | 0.95 | EPHX1 (0.49) | EPHX1USP30ALDH1A1MAPTNPC1 | |
| SCHEMBL28779683 | 0.91 | USP30 (0.48) | EPHX1USP30ALDH1A1MAPTKEAP1 | |
| SCHEMBL28779682 | 0.91 | USP30 (0.48) | EPHX1USP30ALDH1A1MAPTKEAP1 | |
| SCHEMBL13696753 | 0.91 | EPHX1 (0.52) | EPHX1USP30ALDH1A1MAPTNPC1 | |
| SCHEMBL25237250 | 0.91 | EPHX1 (0.52) | EPHX1USP30ALDH1A1MAPTNPC1 | |
| SCHEMBL18556969 | 0.91 | EPHX1 (0.52) | EPHX1USP30ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |