Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.45 |
| ▸ | MDM4 | O15151 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28969076 | 1.00 | SLC17A5 (0.45) | SLC17A5MDM4TP53TNFNPC1 | |
| SCHEMBL30306867 | 1.00 | SLC17A5 (0.45) | SLC17A5MDM4TP53TNFNPC1 | |
| SCHEMBL30306805 | 0.90 | HDAC1 (0.40) | SLC17A5MDM4TP53TNFNPC1 | |
| SCHEMBL30306748 | 0.88 | TLR2 (0.43) | ALDH1A1 | |
| SCHEMBL20526770 | 0.85 | MDM4 (0.47) | SLC17A5MDM4TP53TNFMDM2 | |
| SCHEMBL20526767 | 0.85 | MDM4 (0.47) | SLC17A5MDM4TP53TNFMDM2 | |
| SCHEMBL20526762 | 0.84 | MDM4 (0.52) | SLC17A5MDM4TP53TNFMDM2 | |
| SCHEMBL20526765 | 0.84 | MDM4 (0.52) | SLC17A5MDM4TP53TNFMDM2 | |
| SCHEMBL32676378 | 0.84 | MDM4 (0.52) | SLC17A5MDM4TP53TNFMDM2 | |
| SCHEMBL20526745 | 0.82 | MDM4 (0.46) | SLC17A5MDM4TP53TNFMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115666553-A | TLR2 modulator compounds, and pharmaceutical compositions and uses thereof | 轴向治疗公司 | 2023-01-31 | — | — | CN | disclosed |