Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amineptine SCHEMBL5783484 | 0.84 | HTR2C (1.00) | HTR2CSLC6A3KMT2ANR1I2OPRM1 | |
| Amineptine SCHEMBL29389410 | 0.84 | HTR2C (1.00) | HTR2CSLC6A3KMT2ANR1I2OPRM1 | |
| Amineptine SCHEMBL34086 | 0.84 | HTR2C (1.00) | HTR2CSLC6A3KMT2ANR1I2OPRM1 | |
| Amineptine SCHEMBL362962 | 0.82 | HTR2C (0.97) | HTR2CSLC6A3KMT2ANR1I2OPRM1 | |
| Amineptine SCHEMBL340428 | 0.82 | HTR2C (0.97) | HTR2CSLC6A3KMT2ANR1I2OPRM1 | |
| SCHEMBL28969660 | 0.79 | BCHE (0.51) | HTR2CSLC6A3KMT2ABCHEACHE | |
| SCHEMBL1491692 | 0.79 | KMT2A (0.69) | HTR2CSLC6A3KMT2ACDC25ACDC25B | |
| SCHEMBL11935647 | 0.77 | ACHE (0.64) | HTR2CSLC6A3KMT2ABCHEACHE | |
| SCHEMBL2254514 | 0.76 | MAPT (0.53) | HTR2CSLC6A3KMT2ABCHEACHE | |
| SCHEMBL353186 | 0.76 | BCHE (0.58) | HTR2CSLC6A3KMT2ABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819423-B | PROTAC compound of adefovir or intermediate thereof, preparation method thereof and application of PROTAC compound in EV71 resistance | 武汉大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-115819423-A | ProTAC compound of Reidesciclovir or intermediate thereof, preparation method thereof and application of anti-EV 71 | 武汉大学 | 2023-03-21 | — | — | CN | disclosed |