Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28970112 | 0.80 | NR1H2 (0.35) | NR1H2MAPTNAMPTGPR119USP2 | |
| SCHEMBL31699764 | 0.79 | ADORA1 (0.40) | NR1H2MAPTKDM4ETHRBGPR119 | |
| SCHEMBL26429393 | 0.78 | USP2 (0.36) | NR1H2MAPTKDM4ETHRBGPR119 | |
| SCHEMBL25199915 | 0.74 | ESR2 (0.42) | NR1H2MAPTUSP2SMN1; SMN2 | |
| SCHEMBL28970100 | 0.73 | NR1H2 (0.37) | NR1H2MAPTKDM4ENAMPTTHRB | |
| SCHEMBL31549248 | 0.72 | USP2 (0.43) | NR1H2MAPTKDM4ETHRBGPR119 | |
| SCHEMBL31700008 | 0.71 | NR1H2 (0.34) | NR1H2MAPTNAMPTTHRBGPR119 | |
| SCHEMBL31699299 | 0.71 | CNR1 (0.36) | NR1H2MAPTNAMPTGPR119USP2 | |
| SCHEMBL21597812 | 0.70 | NR1H2 (0.44) | NR1H2MAPTKDM4ENAMPTTHRB | |
| SCHEMBL950867 | 0.70 | NR1H2 (0.44) | NR1H2MAPTKDM4ENAMPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806561-A | JAK3 selective inhibitors and uses thereof | 南京药石科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |