Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28970112 | 0.79 | NR1H2 (0.35) | NR1H2PREPDDB1CRBNGPR119 | |
| SCHEMBL5720840 | 0.77 | NR1H2 (0.40) | NR1H2DDB1CRBNUSP2SMN1; SMN2 | |
| SCHEMBL23794838 | 0.75 | NR1H2 (0.43) | NR1H2PREPDDB1CRBNGPR119 | |
| SCHEMBL20067497 | 0.75 | HCAR2 (0.49) | — | |
| SCHEMBL31699304 | 0.75 | HCAR2 (0.49) | — | |
| SCHEMBL16924576 | 0.73 | POLB (0.36) | NR1H2PREPGPR119MAPTUSP2 | |
| SCHEMBL28970119 | 0.73 | NR1H2 (0.35) | NR1H2PREPGPR119KDM4EMAPT | |
| SCHEMBL22069219 | 0.72 | DDB1 (0.36) | NR1H2PREPDDB1CRBNGPR119 | |
| SCHEMBL950867 | 0.71 | NR1H2 (0.44) | NR1H2DDB1CRBNGPR119KDM4E | |
| SCHEMBL21597812 | 0.71 | NR1H2 (0.44) | NR1H2DDB1CRBNGPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806561-A | JAK3 selective inhibitors and uses thereof | 南京药石科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |