Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34469116 | 1.00 | NR1H2 (0.48) | NR1H2NAMPTMEN1KMT2AACACB | |
| SCHEMBL3061206 | 0.81 | PSEN1 (0.48) | NR1H2NAMPTMEN1KMT2APSEN1 | |
| SCHEMBL30895177 | 0.80 | NR1H2 (0.49) | NR1H2NAMPTMEN1KMT2AACACB | |
| SCHEMBL6890800 | 0.78 | NR1H2 (0.62) | NR1H2NAMPTACACBPSEN1PSEN2 | |
| SCHEMBL29385334 | 0.76 | MEN1 (0.39) | NR1H2NAMPTMEN1KMT2APTPN1 | |
| SCHEMBL23794828 | 0.76 | NR1H2 (0.39) | NR1H2NAMPTMEN1KMT2AACACB | |
| SCHEMBL26260560 | 0.76 | NR1H2 (0.39) | NR1H2NAMPTMEN1KMT2AACACB | |
| SCHEMBL34469262 | 0.75 | MEN1 (0.41) | NR1H2MEN1KMT2APTPN1GPR119 | |
| SCHEMBL23868265 | 0.75 | MEN1 (0.39) | NR1H2MEN1KMT2APTPN1MAPK1 | |
| SCHEMBL1018783 | 0.75 | NR1H2 (0.58) | NR1H2NAMPTACACBPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115806561-A | JAK3 selective inhibitors and uses thereof | 南京药石科技股份有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-114057739-A | Diazepinone derivatives and their use in the treatment of hepatitis b infections | 诺维拉治疗公司 | 2022-02-18 | — | — | CN | disclosed |