Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 9/20 | 0.43 |
| ▸ | GLB1 | P16278 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.43 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29716692 | 0.82 | — | — | |
| SCHEMBL462863 | 0.82 | — | — | |
| SCHEMBL505753 | 0.82 | — | — | |
| SCHEMBL1313595 | 0.82 | — | — | |
| SCHEMBL505465 | 0.82 | — | — | |
| SCHEMBL505752 | 0.82 | — | — | |
| SCHEMBL462864 | 0.82 | — | — | |
| SCHEMBL13906097 | 0.81 | CA1 (0.52) | GBA1GLB1GAAPYGLGBA2 | |
| SCHEMBL28316228 | 0.81 | CA1 (0.52) | GBA1GLB1GAAPYGLGBA2 | |
| SCHEMBL12561505 | 0.81 | CA1 (0.52) | GBA1GLB1GAAPYGLGBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010506-B1 | DIAZEPAN DERIVATIVES MODULATORS OF CHEMOKINE RECEPTORS | HOFFMANN LA ROCHE (CH) | 2010-08-04 | — | — | EP | disclosed |