Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | ACR | P10323 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28971309 | 0.93 | KDM4E (0.40) | KDM4EKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28971338 | 0.91 | PRSS1 (0.40) | KDM4EKMT2AMEN1SMN1; SMN2PRSS1 | |
| SCHEMBL28971250 | 0.91 | HIF1A (0.37) | KDM4EKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL28971254 | 0.90 | KMT2A (0.39) | KDM4EKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL28971313 | 0.87 | KMT2A (0.42) | KMT2AMEN1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL28971281 | 0.87 | KDM4E (0.40) | KDM4EKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL740580 | 0.86 | KDM4E (0.48) | KDM4EKMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL3123277 | 0.86 | HTT (0.43) | KDM4ENPC1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL28971258 | 0.85 | MAPT (0.40) | KMT2AMEN1NPC1MAPTTP53 | |
| Ammonia Solution, Strong SCHEMBL27964628 | 0.85 | HTT (0.42) | KDM4ENPC1SMN1; SMN2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650929-B | Ester compound containing isoxazoline, preparation method and application | 西北农林科技大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-115650929-A | Isoxazoline-containing ester compound, preparation method and application | 西北农林科技大学 | 2023-01-31 | — | — | CN | disclosed |