Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28971250 | 0.93 | HIF1A (0.37) | KDM4EHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28971302 | 0.93 | KDM4E (0.38) | KDM4EHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28971338 | 0.93 | PRSS1 (0.40) | KDM4EHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28971313 | 0.90 | KMT2A (0.42) | HTTKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28971281 | 0.89 | KDM4E (0.40) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28971254 | 0.87 | KMT2A (0.39) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28971297 | 0.87 | KMT2A (0.36) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL740580 | 0.87 | KDM4E (0.48) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28971314 | 0.85 | KMT2A (0.39) | KDM4EHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL16274185 | 0.85 | RECQL (0.43) | KDM4EHTTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650929-B | Ester compound containing isoxazoline, preparation method and application | 西北农林科技大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-115650929-A | Isoxazoline-containing ester compound, preparation method and application | 西北农林科技大学 | 2023-01-31 | — | — | CN | disclosed |