Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25258088 | 1.00 | HDAC1 (0.50) | HDAC1HDAC6CYP2C19CYP1A2GRIN1 | |
| SCHEMBL25305510 | 1.00 | HDAC1 (0.50) | HDAC1HDAC6CYP2C19CYP1A2GRIN1 | |
| SCHEMBL24072831 | 0.91 | HDAC1 (0.47) | HDAC1HDAC6CYP2C19CYP1A2GRIN1 | |
| SCHEMBL30474057 | 0.91 | HDAC1 (0.47) | HDAC1HDAC6CYP2C19CYP1A2GRIN1 | |
| SCHEMBL24073669 | 0.91 | HDAC1 (0.47) | HDAC1HDAC6CYP2C19CYP1A2GRIN1 | |
| SCHEMBL30230922 | 0.89 | HDAC1 (0.43) | HDAC1HDAC6RIPK1FAAHPIM1 | |
| SCHEMBL30060169 | 0.89 | HDAC1 (0.43) | HDAC1HDAC6RIPK1FAAHPIM1 | |
| SCHEMBL25258959 | 0.89 | HDAC1 (0.50) | HDAC1HDAC6CYP2C19CYP1A2GRIN1 | |
| SCHEMBL24073559 | 0.87 | HDAC1 (0.49) | HDAC1HDAC6CYP2C19CYP1A2GRIN1 | |
| SCHEMBL24072829 | 0.87 | HDAC1 (0.49) | HDAC1HDAC6CYP2C19CYP1A2GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667252-A | N- (1-cyano-pyrrolidin-3-yl) -5- (3- (trifluoromethyl) phenyl) oxazole-2-carboxamide derivatives and corresponding oxadiazole derivatives as USP30 inhibitors for the treatment of mitochondrial dysfunction | 特殊治疗有限公司 | 2023-01-31 | — | — | CN | disclosed |