Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | PIM1 | P11309 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30230922 | 1.00 | HDAC1 (0.43) | HDAC1HDAC6FAAHPIM1MAPT | |
| SCHEMBL30061997 | 0.91 | HDAC1 (0.41) | HDAC1HDAC6FAAHPIM1MAPT | |
| SCHEMBL30062624 | 0.91 | HDAC1 (0.41) | HDAC1HDAC6FAAHPIM1MAPT | |
| SCHEMBL25258088 | 0.89 | HDAC1 (0.50) | HDAC1HDAC6FAAHPIM1RIPK1 | |
| SCHEMBL25305510 | 0.89 | HDAC1 (0.50) | HDAC1HDAC6FAAHPIM1RIPK1 | |
| SCHEMBL28971352 | 0.89 | HDAC1 (0.50) | HDAC1HDAC6FAAHPIM1RIPK1 | |
| SCHEMBL30060139 | 0.88 | HDAC1 (0.42) | HDAC1HDAC6FAAHPIM1MAPT | |
| SCHEMBL30060110 | 0.88 | HDAC1 (0.42) | HDAC1HDAC6FAAHPIM1MAPT | |
| SCHEMBL25215127 | 0.87 | HDAC1 (0.39) | HDAC1HDAC6FAAHPIM1 | |
| SCHEMBL25215715 | 0.86 | HDAC1 (0.38) | HDAC1HDAC6FAAHPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461340-A | N-cyanopyrrolidines having activity as USP30 inhibitors | 特殊治疗有限公司 | 2022-12-09 | — | — | CN | disclosed |