⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10308344 | 0.79 | KDM4E (0.33) | — | |
| SCHEMBL7910108 | 0.74 | HMGCR (0.33) | — | |
| SCHEMBL17503248 | 0.73 | CYP2C19 (0.41) | — | |
| SCHEMBL7346515 | 0.72 | — | — | |
| SCHEMBL7917694 | 0.72 | PIK3CD (0.46) | — | |
| SCHEMBL116713 | 0.72 | — | — | |
| SCHEMBL11913942 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL10847286 | 0.71 | — | — | |
| SCHEMBL10137806 | 0.71 | CPT2 (0.48) | — | |
| SCHEMBL8861303 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725582-A | IMMUNE RESPONSE ENHANCERS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1988-02-16 | — | — | US | claimed |
| CN-102958947-B | Polymerization process with in-situ initiator formation | AKZO NOBEL CHEMICALS INT BV | 2014-11-26 | — | — | CN | disclosed |
| CN-102958947-A | Polymerization process with in-situ initiator formation | AKZO NOBEL CHEMICALS INT BV | 2013-03-06 | — | — | CN | disclosed |
| US-7687510-B2 | Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes | BAYER HEALTHCARE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| CN-101322241-A | Semiconductor device and method for manufacturing the same | FUJITSU LTD (JP) | 2008-12-10 | — | — | CN | disclosed |
| US-20060160801-A1 | Pyrimidinone derivaties as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-20 | — | — | US | disclosed |
| CN-1221013-C | Gasification supplying method | JAPAN PIONEER CORP (JP) | 2005-09-28 | — | — | CN | disclosed |
| CN-1407604-A | Gasification supplying method | JAPAN PIONEER CORP (JP) | 2003-04-02 | — | — | CN | disclosed |